W. Schmidt
D. Quosdorf
S. Siewert
U. Hinze
B. N. Chichkov
M. Brede
A. Leder
R. F. Guthoff
K.-P. Schmitz

Micro Particle-Image-Velocimetry for characterization of a micro-mechanical valve in a glaucoma implant

Conference of the German Society for Biomedical Engineering (BMT)
16.-19. September
Jena
2012
Type: Konferenzbeitrag
Abstract
Controlled reduction of intraocular pressure is a main issue in treatment of glaucoma. A novel approach of glaucoma implant is based on a silicone microstent draining the aqueous humor from the anterior chamber of the eye into the suprachoroidal space. The paper presents micro particle-image velocimetry as a method to characterize the fluidmechanical function of the micromechanical valve. The current field around the valve region was measured quantitatively. The flow velocity ranged from 1E-6 to 2.5E-2 m/s depending on pressure difference. The valve opening pressure was Δp=4 mmHg indicated by an elevation of flow velocity by almost two orders of magnitude at this pressure difference. Further improvements of μPIV method will be a powerful tool for development and in particular for investigation of flow phenomena at pressure differences around the opening pressure as well as for new valve designs.