We present our investigations into the design and fabrication of a complex shape, readily assembled micro check-valve using the two-photon polymerization technique and a hybrid material. A computational fluid dynamics study has been carried out in order to evaluate the flow performance of the valve under blood pressures exhibited in healthy human veins. The fabricated micro-valves exhibit good dimensional accuracy when compared to the CAD-created valve design and the capability of an internal moving component to perform its intended function.