Carbon fibre reinforced plastic (CFRP) is a well-established material in modern aerospace products. While the majority of primary structural components contains a thermoset matrix material, secondary components are increasingly made of thermoplastic matrix systems. Due to their superb performance and advantageous production properties, thermoplastics matrices are now also pushing into primary structural applications like fuselage, cowlings, and wings. These structures are subject to an increased risk of damage during operation. Thus, repair strategies that address thermoplastic CFRP come to the fore. The repair by conventional tooling faces challenges that result from the thermoplastics’ abilities to melt, which cause the tools to clog and decrease process efficiency. Laser ablation poses an alternative approach allowing precise material removal without material related wear and thus a constant process quality. This study demonstrates process efficiency of a laser ablation process on a CFRP with polyphenylene sulphide (PPS) matrix and the used processing parameters on the repair quality.