Gold nanoparticles are of high interest in versatile applications like medicine, biochemistry or biology. Due to its special optical properties like plasmon-resonance-enhanced absorption or light scattering it is possible to mark and sort biological cells with functionalized gold nanoparticles.

 

Within this project, a sensitive optical detection method for gold-nanoparticle-incorporated cells will be established. In detail, a high-throughput flow of gold-nanoparticle-marked cells will be analyzed by laser spectroscopy and sorted into fractions. The work will include modification of a cell sorting device, optical set-up and determination of detection limit of gold nanoparticles incorporated in cells and subsequent automatization to a continuous process.

 

Research and development within this project will be done in cooperation with the Friedrich-Loeffler-Institute Mariensee.

 

The LZH group Nanomaterials is a interdisciplinary working group of physiccists, biologists, engineers and chemists who focus on generation of nanomaterials by laser ablation in liquids. By this manner nanoparticles of high purity and almost any materials are accessible.